FMO5 antibody (N-Term)

Catalog No. ABIN3042656

The Rabbit Polyclonal anti-FMO5 antibody has been validated for WB. It is suitable to detect FMO5 in samples from Human.

Quick Overview for FMO5 antibody (N-Term) (ABIN3042656)

Target: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMO5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FMO5 Antibody

Binding Specificity: AA 77-90, N-Term

Purpose: Anti-FMO5 Antibody Picoband®

Sequence: DHYPNFMHNA QVLE

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-FMO5 Antibody (ABIN3042656). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human FMO5, different from the related rat sequence by one amino acid, and different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Gelb, B. D., Zhang, J., Cotter, P. D., Gershin, I. F., Desnick, R. J. Physical mapping of the human connexin 40 (GJA5), flavin-containing monooxygenase 5, and natriuretic peptide receptor A genes on 1q21. Genomics 39: 409-411, 1997. 2. Miller, M. M., James, R. A., Richer, J. K., Gordon, D. F., Wood, W. M., Horwitz, K. B.Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity. J. Clin. Endocr. Metab. 82: 2956-2961, 1997. 3. Overby, L. H., Buckpitt, A. R., Lawton, M. P., Atta-Asafo-Adjei, E., Schulze, J., Philpot, R. M. Characterization of flavin-containing monooxygenase 5(FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog. Arch. Biochem. Biophys. 317: 275-284, 1995.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FMO5

Target: FMO5 (Flavin Containing Monooxygenase 5 (FMO5))

Alternative Name: FMO5

Background:

Synonyms: Dimethylaniline monooxygenase [N-oxide-forming] 5,1.14.13.8,Dimethylaniline oxidase 5,Hepatic flavin-containing monooxygenase 5,FMO 5,FMO5,

Tissue Specificity: Expressed in fetal and adult liver.

Background: Dimethylaniline monooxygenase[N-oxide-forming] 5 also known as FMO 5 is an enzyme that in humans is encoded by the FMO5 gene. By fluorescence in situ hybridization, this gene was assigned to human chromosome 1q21.1. FMO5 is not an efficient drug-metabolizing enzyme and that it may have an alternative physiologic role. FMO5 transcripts play an important role in progesterone-regulated in breast cancer cells specifically under the control of the progesterone receptor B-isoform.

Sequence Similarities: Belongs to the FMO family.

Molecular Weight: 60 kDa

UniProt: P49326