Thrombospondin 2 antibody (Middle Region)

Catalog No. ABIN3042702

Product Details anti-Thrombospondin 2 Antibody

Target: Thrombospondin 2 (THBS2)

Binding Specificity: AA 637-655, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombospondin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Anti-Thrombospondin 2/THBS2 Antibody Picoband®

Sequence: EAAKTEKQVC EPENPCKDK

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Thrombospondin 2/THBS2 Antibody (ABIN3042702). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Thrombospondin 2, different from the mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Hirose Y, Chiba K, Karasugi T, Nakajima M, Kawaguchi Y, Mikami Y, Furuichi T, Mio F, Miyake A, Miyamoto T, Ozaki K, Takahashi A, Mizuta H, Kubo T, Kimura T, Tanaka T, Toyama Y, Ikegawa S (May 2008). "A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation". Am J Hum Genet 82 (5): 1122-9. 2. Hirose, Y., Chiba, K., Karasugi, T., Nakajima, M., Kawaguchi, Y., Mikami, Y., Furuichi, T., Mio, F., Miyake, A., Miyamoto, T., Ozaki, K., Takahashi, A., Mizuta, H., Kubo, T., Kimura, T., Tanaka, T., Toyama, Y., Ikegawa, S.A functional polymorphism in THBS2 that affects alternative splicing and MMP binding is associated with lumbar-disc herniation.Am. J. Hum. Genet.82: 1122-1129, 2008. 3. Entrez Gene: THBS2 thrombospondin 2".

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Thrombospondin 2

Target: Thrombospondin 2 (THBS2)

Alternative Name: THBS2 (THBS2 Products)

Background:

Synonyms: Thrombospondin-2,THBS2,TSP2,

Tissue Specificity: High expression in invertebral disk tissue. .

Background: Thrombospondin-2 (THBS2) is a protein that in humans is encoded by the THBS2 gene. The protein encoded by this gene belongs to the thrombospondin family. The THBS2 is mapped to 6q27 and it is located on chromosome 17. The gene was transcribed in fibroblasts, smooth muscle cells, and an osteosarcoma cell line. It functions as a protein inhibitor of tumor growth and angiogenesis and modulates the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.

Sequence Similarities: Belongs to the thrombospondin family.

Molecular Weight: 160 kDa

UniProt: P35442