Apolipoprotein D antibody (C-Term)

Catalog No. ABIN3042724

This Rabbit Polyclonal antibody specifically detects Apolipoprotein D in WB. It exhibits reactivity toward Human.

Quick Overview for Apolipoprotein D antibody (C-Term) (ABIN3042724)

Target: Apolipoprotein D (APOD)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apolipoprotein D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Apolipoprotein D Antibody

Binding Specificity: AA 172-189, C-Term

Purpose: Anti-Apolipoprotein D/APOD Antibody Picoband®

Sequence: IDVKKMTVTD QVNCPKLS

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Apolipoprotein D/APOD Antibody (ABIN3042724). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Apolipoprotein D.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Drayna, D. T., McLean, J. W., Wion, K. L., Trent, J. M., Drabkin, H. A., Lawn, R. M. Human apolipoprotein D gene: gene sequence, chromosome localization, and homology to the alpha-2mu-globulin superfamily. DNA 6: 199-204, 1987. 2. Drayna, D., Fielding, C., McLean, J., Baer, B., Castro, G., Chen, E., Comstock, L., Henzel, W., Kohr, W., Rhee, L., Wion, K., Lawn, R.Cloning and expression of human apolipoprotein D cDNA.J. Biol. Chem.261: 16535-16539, 1986. 3. Appari M, Werner R, Wünsch L, Cario G, Demeter J, Hiort O, Riepe F, Brooks JD, Holterhus PM (June 2009). "Apolipoprotein D (APOD) is a putative biomarker of androgen receptor function in androgen insensitivity syndrome". J. Mol. Med. 87 (6): 623-32.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Apolipoprotein D

Target: Apolipoprotein D (APOD)

Alternative Name: APOD

Background:

Synonyms: Apolipoprotein D,Apo-D,ApoD,APOD,

Tissue Specificity: Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears.

Background: Apolipoprotein D (Apo-D) is a protein that in humans, encoded by the APOD gene. Being a member of the alpha (2 mu)-microglobulin superfamily of carrier proteins, Apo-D is also known as lipocalin.The gene has been localized to the p14.2----qter region of human chromosome 3. It is a glycoprotein of estimated molecular weight 33,000 Da. The Apo-D encoded a protein of 169 amino acid residue.It has been detected in human liver, intestine, pancreas, kidney, placenta, adrenal, spleen, and fetal brain tissue. For its features, Apo-D has been a biomarker of androgen insensitivity syndrome (AIS).

Sequence Similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Molecular Weight: 30 kDa

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling