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CYP1B1 antibody (AA 255-480)

CYP1B1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042785
  • Target See all CYP1B1 Antibodies
    CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
    Binding Specificity
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 255-480
    Reactivity
    • 44
    • 32
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 57
    • 2
    Rabbit
    Clonality
    • 56
    • 3
    Polyclonal
    Conjugate
    • 26
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP1B1 antibody is un-conjugated
    Application
    • 41
    • 14
    • 10
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Cytochrome P450 1B1(CYP1B1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Cytochrome P450 1B1(CYP1B1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: cytochrome P450, family 1, subfamily B, polypeptide 1
    Protein Name: Cytochrome P450 1B1
    Purification
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human CYP1B1 recombinant protein (Position: R255-L480). Human CYP1B1 shares 85.4% and 84.5% amino acid (aa) sequence identity with mouse and rat CYP1B1, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product CYP1B1 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
    Alternative Name
    CYP1B1 (CYP1B1 Products)
    Synonyms
    CP1B antibody, CYPIB1 antibody, GLC3A antibody, P4501B1 antibody, P4501b1 antibody, CYP1B1 antibody, CYP1B antibody, zgc:136223 antibody, cytochrome P450 family 1 subfamily B member 1 antibody, cytochrome P450, family 1, subfamily b, polypeptide 1 antibody, cytochrome P450, family 1, subfamily B, polypeptide 1 antibody, cytochrome P450 1B1 antibody, CYP1B1 antibody, Cyp1b1 antibody, cyp1b1 antibody, LOC100719054 antibody
    Background
    Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene. CYP1B1 belongs to the the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

    Synonyms: Aryl hydrocarbon hydroxylase antibody|CP1B antibody|CP1B1_HUMAN antibody|Cyp1b1 antibody| CYPIB1 antibody|Cytochrome P450 1B1 antibody|Cytochrome P450 family 1 subfamily B polypeptide 1 antibody|Cytochrome P450 subfamily I (dioxin inducible) polypeptide 1 (glaucoma 3 primary infantile) antibody|Flavoprotein linked monooxygenase antibody| GLC3A antibody|Microsomal monooxygenase antibody|P4501B1 antibody|Xenobiotic monooxygenase antibody
    Gene ID
    1545
    UniProt
    Q16678
    Pathways
    Steroid Hormone Biosynthesis
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