PLG antibody (AA 103-352)
Quick Overview for PLG antibody (AA 103-352) (ABIN3042791)
Target
See all PLG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 103-352
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Purpose
- Anti-Angiostatin K1-3/PLG Antibody
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Characteristics
- Anti-Angiostatin K1-3/PLG Antibody (ABIN3042791). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogen
- E. coli-derived human Angiostatin K1-3 recombinant protein (Position: C103-C352).
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Isotype
- IgG
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Application Notes
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Human
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Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free or No BSA in your order note.
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Preservative
- Sodium azide, Without preservative
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PLG (Plasminogen (PLG))
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Alternative Name
- PLG
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Background
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Synonyms: Plasminogen,3.4.21.7,Plasmin heavy chain A,Activation peptide,Angiostatin,Plasmin heavy chain A, short form,Plasmin light chain B,PLG,
Tissue Specificity: Present in plasma and many other extracellular fluids. It is synthesized in the liver.
Background: Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50 = 70nM) relative to kringles 1-4 (ED50 = 135nM).
Sequence Similarities: Belongs to the peptidase S1 family. Plasminogen subfamily.
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Molecular Weight
- 95 kDa
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UniProt
- P00747
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Pathways
- Complement System, Lipid Metabolism
Target
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