LPP antibody (Middle Region)

Catalog No. ABIN3042935

The Rabbit Polyclonal anti-LPP antibody has been validated for WB. It is suitable to detect LPP in samples from Human.

Quick Overview for LPP antibody (Middle Region) (ABIN3042935)

Target: LPP (Lipoma-preferred partner (LPP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LPP Antibody

Binding Specificity: AA 291-307, Middle Region

Purpose: Anti-Lipoma-preferred partner LPP Antibody Picoband®

Sequence: PNQGRYYEGY YAAGPGY

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Lipoma-preferred partner LPP Antibody (ABIN3042935). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human LPP.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Daheron, L., Veinstein, A., Brizard, F., Drabkin, H., Lacotte, L., Guilhot, F., Larsen, C. J., Brizard, A., Roche, J. Human LPP gene is fused to MLL in a secondary acute leukemia with a t(3,11)(q28,q23). Genes Chromosomes Cancer 31: 382-389, 2001. 2. Petit, M. M. R., Mols, R., Schoenmakers, E. F. P. M., Mandahl, N., Van de Ven, W. J. M. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. Genomics 36: 118-129, 1996.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LPP

Target: LPP (Lipoma-preferred partner (LPP))

Alternative Name: LPP

Background:

Synonyms: Lipoma-preferred partner,LIM domain-containing preferred translocation partner in lipoma,LPP,

Tissue Specificity: Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes. .

Background: LPP (Lim Domain-Containing Preferred Translocation Partner in Lipoma) is a protein that in humans is encoded by the LPP gene. Petit et al. (1996) commented that the LPP-encoded protein should be classified as a novel member of the group 3 proteins of the LIM protein gene family. By partial cDNA cloning, Petit et al. (1996) established features of the genetic organization of LPP. The gene was found to span a genomic region of over 400 kb. By FISH and Southern blot analyses, Daheron et al. (2001) identified a rearrangement in the mixed lineage leukemia gene due to a novel t (3,11) (q28,q23) translocation in a patient who developed acute myeloid leukemia of the M5 type 3 years after treatment for a follicular lymphoma.

Sequence Similarities: Belongs to the zyxin/ajuba family.

Molecular Weight: 80 kDa

UniProt: Q93052