Surfactant Protein A1 antibody (C-Term)

Catalog No. ABIN3043063

This Rabbit Polyclonal antibody specifically detects Surfactant Protein A1 in WB. It exhibits reactivity toward Human and Rat and has been mentioned in 3+ publications.

Quick Overview for Surfactant Protein A1 antibody (C-Term) (ABIN3043063)

Target: Surfactant Protein A1 (SFTPA1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfactant Protein A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Surfactant Protein A1 Antibody

Binding Specificity: AA 221-236, C-Term

Purpose: Anti-SFTPA1 Antibody Picoband®

Sequence: KEQCVEMYTD GQWNDR

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SFTPA1 Antibody (ABIN3043063). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1, different from the rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Moore, K. J., D'Amore-Bruno, M. A., Korfhagen, T. R., Glasser, S. W., Whitsett, J. A., Jenkins, N. A., Copeland, N. G. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics 12: 388-393, 1992. 2. Ramet, M., Lofgren, J., Albo, O.-P., Hallman, M. Surfactant protein-A gene locus associated with recurrent otitis media. J. Pediat. 138: 266-268, 2001.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year and at 4°C for one month from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

References for anti-Surfactant Protein A1 antibody (ABIN3043063)

Hu, Wang, Rao, Zhao, Yang, Hu, He, Xia, Liu, Zhen, Di, Xie, Xia, Zhu: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).

Zhou, Chen, Jiang, Feng, Han: "Effects of bone marrow-derived mesenchymal stem cells transfected with survivin on pulmonary fibrosis in mice." in: Experimental and therapeutic medicine, Vol. 10, Issue 5, pp. 1857-1864, (2015) (PubMed).

Wu, You, Ma, Li, Yuan, Li, Ye, Liu, Yao, Chen, Lai, Yang: "Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice." in: PLoS ONE, Vol. 8, Issue 5, pp. e62827, (2013) (PubMed).

Target Details for Surfactant Protein A1

Target: Surfactant Protein A1 (SFTPA1)

Alternative Name: SFTPA1

Background:

Synonyms: Pulmonary surfactant-associated protein A1,PSP-A,PSPA,SP-A,SP-A1,35 kDa pulmonary surfactant-associated protein,Alveolar proteinosis protein,Collectin-4,SFTPA1,COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B,

Tissue Specificity: Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.

Background: Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14.1. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

Sequence Similarities: Belongs to the SFTPA family.

Molecular Weight: 26-35 kDa