Lipocalin 1 antibody (Middle Region)

Catalog No. ABIN3043125

This anti-Lipocalin 1 antibody is a Rabbit Polyclonal antibody detecting Lipocalin 1 in WB and IHC. Suitable for Human.

Quick Overview for Lipocalin 1 antibody (Middle Region) (ABIN3043125)

Target: Lipocalin 1 (LCN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipocalin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Lipocalin 1 Antibody

Binding Specificity: AA 110-124, Middle Region

Purpose: Anti-Lipocalin-1 LCN1 Antibody Picoband®

Sequence: HVKDHYIFYC EGELH

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Lipocalin-1 LCN1 Antibody (ABIN3043125). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human LCN1.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Baumgartner, M., Holzfeind, P., Redl, B. Assignment of the gene for human tear prealbumin (LCN1), a member of the lipocalin superfamily, to chromosome 8q24. Cytogenet. Cell Genet. 65: 101-103, 1994. 2. Blaker, M., Kock, K., Ahlers, C., Buck, F., Schmale, H. Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands. Biochim. Biophys. Acta 1172: 131-137, 1993. 3. Glasgow BJ, Abduragimov AR, Gasymov OK, Yusifov TN (2003). "Tear lipocalin: structure, function and molecular mechanisms of action". Adv. Exp. Med. Biol. 506 (Pt A): 555-65.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Lipocalin 1

Target: Lipocalin 1 (LCN1)

Alternative Name: LCN1

Background:

Synonyms: Lipocalin-1,Tear lipocalin,Tlc,Tear prealbumin,TP,Von Ebner gland protein,VEG protein,LCN1,VEGP,

Tissue Specificity: Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.

Background: Lipocalin-1 (LCN1), also known as PREALBUMIN, TEAR or VEGP, is a protein that in humans is encoded by the LCN1 gene. Lipocalin-1 is a member of the lipocalin family of small secretory proteins, which is mapped on 9q34.3. Lipocalin-1 is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. It may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. LCN1 inhibits the cysteine-protease papain in vitro, similar to cystatins. And LCN1 plays a role in the nonimmunologic defense and in the control of inflammatory processes in oral and ocular tissues. The investigations presented the first clear evidence that LCN1 is induced in infection or inflammation and supported the idea that this lipocalin functions as a physiologic protection factor of epithelia in vivo.

Molecular Weight: 19 kDa

UniProt: P31025