Surfactant Protein A1 antibody (C-Term)

Catalog No. ABIN3043205

The Rabbit Polyclonal anti-Surfactant Protein A1 antibody has been validated for WB and IHC. It is suitable to detect Surfactant Protein A1 in samples from Rat and Mouse. There are 5+ publications available.

Quick Overview for Surfactant Protein A1 antibody (C-Term) (ABIN3043205)

Target: Surfactant Protein A1 (SFTPA1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfactant Protein A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Surfactant Protein A1 Antibody

Binding Specificity: AA 233-248, C-Term

Purpose: Anti-SFTPA1 Antibody Picoband®

Sequence: WNDKGCLQYR LAICEF

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SFTPA1 Antibody (ABIN3043205). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse SFTPA1, identical to the related rat sequence.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. Moore, K. J., D'Amore-Bruno, M. A., Korfhagen, T. R., Glasser, S. W., Whitsett, J. A., Jenkins, N. A., Copeland, N. G. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics 12: 388-393, 1992. 2. Ramet, M., Lofgren, J., Albo, O.-P., Hallman, M. Surfactant protein-A gene locus associated with recurrent otitis media. J. Pediat. 138: 266-268, 2001.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Surfactant Protein A1 antibody (ABIN3043205)

Ostermann, Seeliger, David, Flasche, Maus, Reinboth, Christmann, Neumann, Brand, Seltmann, Bühling, Paton, Roth, Vogl, Viemann, Welte, Maus: "S100A9 is indispensable for survival of pneumococcal pneumonia in mice." in: PLoS pathogens, Vol. 19, Issue 7, pp. e1011493, (2023) (PubMed).

Ostermann, Maus, Stolper, Schütte, Katsarou, Tumpara, Pich, Mueller, Janciauskiene, Welte, Maus: "Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Hu, Wang, Rao, Zhao, Yang, Hu, He, Xia, Liu, Zhen, Di, Xie, Xia, Zhu: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).

Zhou, Chen, Jiang, Feng, Han: "Effects of bone marrow-derived mesenchymal stem cells transfected with survivin on pulmonary fibrosis in mice." in: Experimental and therapeutic medicine, Vol. 10, Issue 5, pp. 1857-1864, (2015) (PubMed).

Wu, You, Ma, Li, Yuan, Li, Ye, Liu, Yao, Chen, Lai, Yang: "Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice." in: PLoS ONE, Vol. 8, Issue 5, pp. e62827, (2013) (PubMed).

Target Details for Surfactant Protein A1

Target: Surfactant Protein A1 (SFTPA1)

Alternative Name: SFTPA1

Background:

Synonyms: Pulmonary surfactant-associated protein A,PSAP,PSP-A,SP-A,Sftpa1,Sftp-1, Sftp1, Sftpa,

Background: Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

Sequence Similarities: Belongs to the SFTPA family.

Molecular Weight: 26-35 kDa

UniProt: P35242