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STXBP2 antibody (N-Term)

STXBP2 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043304
  • Target See all STXBP2 Antibodies
    STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
    Binding Specificity
    • 8
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 184-215, N-Term
    Reactivity
    • 38
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 38
    • 1
    • 1
    Rabbit
    Clonality
    • 39
    • 1
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STXBP2 antibody is un-conjugated
    Application
    • 31
    • 19
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Syntaxin-binding protein 2(STXBP2) detection. Tested with WB in Human,Mouse,Rat.
    Sequence
    QEYPAIRYRK GPEDTAQLAH AVLAKLNAFK AD
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Syntaxin-binding protein 2(STXBP2) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: syntaxin binding protein 2
    Protein Name: Syntaxin-binding protein 2
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human STXBP2 (184-215aa QEYPAIRYRKGPEDTAQLAHAVLAKLNAFKAD), different from the related mouse and rat sequences by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product STXBP2 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
    Alternative Name
    STXBP2 (STXBP2 Products)
    Synonyms
    zgc:85807 antibody, FHL5 antibody, Hunc18b antibody, MUNC18-2 antibody, UNC18-2 antibody, UNC18B antibody, pp10122 antibody, C79054 antibody, Munc-18-2 antibody, Munc-18b antibody, Munc18b antibody, Sxtbp2 antibody, Sxtp2 antibody, Unc18-2 antibody, Unc18b antibody, muSec1 antibody, MUNC-18-2 antibody, syntaxin binding protein 2 antibody, stxbp2 antibody, STXBP2 antibody, Stxbp2 antibody
    Background
    Syntaxin-binding protein 2, also known as UNC18B, is a protein that in humans is encoded by the STXBP2 gene. The STXBP2 gene is mapped to human chromosome 19p13.3-p13.2 and to the proximal arm of mouse chromosome 8. And this gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Additionally, UNC18B is expressed predominantly as a 2.4-kb message in placenta, lung, liver, kidney, and pancreas, as well as in peripheral blood lymphocytes. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

    Synonyms: FHL5 antibody|Hunc18b antibody|MUNC18 2 antibody|pp10122 antibody|Protein unc-18 homolog 2 antibody|Protein unc-18 homolog B antibody| STXB2_HUMAN antibody|Stxbp2 antibody|syntaxin binding protein 2 antibody|Syntaxin-binding protein 2 antibody|Unc-18B antibody|UNC18 2 antibody|Unc18-2 antibody|UNC18B antibody
    Gene ID
    6813
    UniProt
    Q15833
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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