Sectm1b antibody (C-Term)

Catalog No. ABIN3043325

The Rabbit Polyclonal anti-Sectm1b antibody is suitable to detect Sectm1b in samples from Mouse. It has been validated for WB.

Quick Overview for Sectm1b antibody (C-Term) (ABIN3043325)

Target: Sectm1b (SECTM1B) (Secreted and Transmembrane 1B (SECTM1B))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details anti-Sectm1b Antibody

Binding Specificity: AA 118-152, C-Term

Purpose: Anti-SECTM1/Sectm1b Antibody

Sequence: KLHGFQAEFK NFNLTVNAAD RQKTEDLPVT KVPDK

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SECTM1/Sectm1b Antibody (ABIN3043325). Tested in WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse SECTM1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Sectm1b

Target: Sectm1b (SECTM1B) (Secreted and Transmembrane 1B (SECTM1B))

Alternative Name: Sectm1b

Background:

Synonyms: Secreted and transmembrane protein 1b,Protein K-12,Sectm1b,K12, Sectm1,

Tissue Specificity: Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers. .

Background: SECTM1B is also known as Sectm1 or K12. Secreted and transmembrane protein 1 is a protein that in humans is encoded by the SECTM1 gene. This gene encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes.

Molecular Weight: 23 kDa

Gene ID: 58210