SNAI3 antibody (Middle Region)

Catalog No. ABIN3043345

This Rabbit Polyclonal antibody specifically detects SNAI3 in WB. It exhibits reactivity toward Human.

Quick Overview for SNAI3 antibody (Middle Region) (ABIN3043345)

Target: SNAI3 (Snail Homolog 3 (SNAI3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAI3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNAI3 Antibody

Binding Specificity: AA 155-178, Middle Region

Purpose: Anti-SNAI3 Antibody Picoband®

Sequence: FHCHKPYHTL AGLARHRQLH CHLQ

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SNAI3 Antibody Picoband® (ABIN3043345). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SNAI3, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Katoh M, Katoh M: Identification and characterization of human SNAIL3 (SNAI3) gene in silico. Int J Mol Med, 2003 Mar.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for SNAI3

Target: SNAI3 (Snail Homolog 3 (SNAI3))

Alternative Name: SNAI3

Background:

Synonyms: Zinc finger protein SNAI3,Protein snail homolog 3,Zinc finger protein 293,SNAI3,ZNF293,

Tissue Specificity: Expressed in platelets (at protein level). .

Background: SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t (16,21) (q24,q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And Human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.

Sequence Similarities: Belongs to the snail C2H2-type zinc-finger protein family.

Molecular Weight: 32 kDa

Gene ID: 333929