MMP10 antibody (C-Term)

Catalog No. ABIN3043406

The Rabbit Polyclonal anti-MMP10 antibody has been validated for WB. It is suitable to detect MMP10 in samples from Human.

Quick Overview for MMP10 antibody (C-Term) (ABIN3043406)

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MMP10 Antibody

Binding Specificity: AA 409-443, C-Term

Purpose: Anti-MMP10 Antibody Picoband®

Sequence: RFDENSQSME QGFPRLIADD FPGVEPKVDA VLQAF

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-MMP10 Antibody Picoband® (ABIN3043406). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MMP10, different from the related mouse sequence by twelve amino acids, and from the related rat sequence by nine amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Jung JY, Warter S, Rumpler Y (1990). "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization". Ann. Genet. 33 (1): 21-3. 2. Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R (July 1988). "The collagenase gene family in humans consists of at least four members". Biochem. J. 253 (1): 187-92.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for MMP10

Target: MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))

Alternative Name: MMP10

Background:

Synonyms: Stromelysin-2,SL-2,3.4.24.22,Matrix metalloproteinase-10,MMP-10,Transin-2,MMP10,STMY2,

Tissue Specificity: Produced by normal alveolar macrophages and granulocytes.

Background: Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Molecular Weight: 54 kDa

Gene ID: 4319

UniProt: P09238