Adiponectin Receptor 1 antibody (N-Term)

Catalog No. ABIN3043520

The Rabbit Polyclonal anti-Adiponectin Receptor 1 antibody is suitable to detect Adiponectin Receptor 1 in samples from Human and Rat. It has been validated for WB, ICC and IF.

Quick Overview for Adiponectin Receptor 1 antibody (N-Term) (ABIN3043520)

Target: Adiponectin Receptor 1 (ADIPOR1)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adiponectin Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Adiponectin Receptor 1 Antibody

Binding Specificity: AA 51-78, N-Term

Purpose: Anti-Adiponectin Receptor 1/ADIPOR1 Antibody

Sequence: EQTCPVPQEE EEEVRVLTLP LQAHHAME

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Adiponectin Receptor 1/ADIPOR1 Antibody (ABIN3043520). Tested in IF, ICC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ADIPOR1, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Adiponectin Receptor 1

Target: Adiponectin Receptor 1 (ADIPOR1)

Alternative Name: ADIPOR1

Background:

Synonyms: Adiponectin receptor protein 1,Progestin and adipoQ receptor family member I,ADIPOR1,PAQR1 , TESBP1A,CGI-45,

Tissue Specificity: Widely expressed (PubMed:16044242). Highly expressed in heart and skeletal muscle (PubMed:12802337). Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337). Weakly expressed in colon, thymus and small intestine (PubMed:12802337). .

Background: ADIPOR1 is known as Adiponectin receptor protein 1. This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.

Sequence Similarities: Belongs to the ADIPOR family.

Molecular Weight: 43 kDa

UniProt: Q96A54

Pathways: AMPK Signaling