FSTL3 antibody (Middle Region)

Catalog No. ABIN3044124

The Rabbit Polyclonal anti-FSTL3 antibody (ABIN3044124) specifically detects FSTL3 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FSTL3 antibody (Middle Region) (ABIN3044124)

Target: FSTL3 (Follistatin-Like 3 (Secreted Glycoprotein) (FSTL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FSTL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FSTL3 Antibody

Binding Specificity: AA 145-159, Middle Region

Purpose: Anti-Follistatin-related protein 3 FSTL3 Antibody

Sequence: ECELRAARCR GHPDL

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Follistatin-related protein 3 FSTL3 Antibody (ABIN3044124). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human FSTL3, different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FSTL3

Target: FSTL3 (Follistatin-Like 3 (Secreted Glycoprotein) (FSTL3))

Alternative Name: FSTL3

Background:

Synonyms: Follistatin-related protein 3,Follistatin-like protein 3,Follistatin-related gene protein,FSTL3,FLRG,UNQ674/PRO1308,

Tissue Specificity: Expressed in a wide range of tissues. .

Background: FSTL3 (Follistatin-Like 3) also known as FLRG or FOLLISTATIN-RELATED GENE, is a member of the follistatin-module protein family, which is composed of extracellular matrix-associated glycoproteins though to act in a paracrine manner to bind morphogens or growth/differentiation factors and regulate their activity during development. The FSTL3 gene extends over 7 kbp and contains 5 exons. By Southern blot analysis of somatic cell hybrids and FISH, Hayette et al. (1998) localized the FSTL3 gene to chromosome 19p13. Using recombinant mouse Fstl3, Tsuchida et al. (2000) found that Fstl3bound both activin and BMP2 and had a higher affinity for activin. Overexpression of Fstl3 inhibited BMP2-induced cell signaling in a reporter assay. In addition to the translocation in a case of B-cell chronic lymphocytic leukemia from which FSTL3 was isolated, Hayette et al. (1998) also observed rearrangement of the FSTL3 gene in a case of B-cell non-Hodgkin lymphoma and in a case of B-cell mantle zone lymphoma, suggesting that FSTL3 may be involved in the leukemogenesis process.

Sequence Similarities: Contains 2 follistatin-like domains.

Molecular Weight: 22-24 kDa

UniProt: O95633