HOXA4 antibody (N-Term)

Catalog No. ABIN3044213

Product Details anti-HOXA4 Antibody

Target: HOXA4 (Homeobox A4 (HOXA4))

Binding Specificity: AA 9-26, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purpose: Anti-Homeobox protein Hox-A4 HOXA4 Antibody Picoband®

Sequence: NSNYIEPKFP PFEEYAQH

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Homeobox protein Hox-A4 HOXA4 Antibody (ABIN3044213). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HOXA4, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Immunocytochemistry , 0.5-1 μg/mL, Human, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". 2. Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". 3. "Entrez Gene: HOXA4 homeobox A4".

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-HOXA4 antibody (ABIN3044213)

Li, Chen, Su, Hu, Li, Elkahloun, Zuo, Gurbuxani, Arnovitz, Weng, Wang, Li, Huang, Neilly, Wang, Jiang, Liu, Jin, Chen: "PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease." in: Cancer research, Vol. 76, Issue 3, pp. 619-29, (2016) (PubMed).

Target Details for HOXA4

Target: HOXA4 (Homeobox A4 (HOXA4))

Alternative Name: HOXA4 (HOXA4 Products)

Background:

Synonyms: Homeobox protein Hox-A4,Homeobox protein Hox-1.4,Homeobox protein Hox-1D,HOXA4,HOX1D,

Tissue Specificity: Embryonic nervous system.

Background: HOXA4 (HOMEOBOX A4), also known as HOX1D or HOMOLOG OF, is a protein that in humans is encoded by the HOXA4 gene, which is also part of the A cluster on chromosome 7. HOXA4 encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Its cytogenetic location is 7q15.2. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.

Sequence Similarities: Belongs to the Antp homeobox family. Deformed subfamily.

Molecular Weight: 46 kDa

UniProt: Q00056