KIT antibody (PE)

Catalog No. ABIN306091

Product Details anti-KIT Antibody (PE)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This KIT antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Recognizes mouse CD117, a 150kD cell surface molecule that is otherwise known as the Kit, or c-kit, receptor. Recognizes an epitope within the extracellular region of CD117. In mice, CD117 is predominantly expressed on multipotent hematopoietic stem cells from the adult bone marrow and fetal liver.

Purification: Protein A purified

Immunogen: IL-3 dependent mast cells.

Type of Immunogen: Cells

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo (1:1)

Usage: Flow Cytometry: Use 5 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: C-Kit / CD117 (KIT Products)

Background: Name/Gene ID: KIT
Subfamily: PDGF Receptor
Family: Protein Kinase

Synonyms: KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen

Gene ID: 3815

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity