S100A7
Reactivity: Human
WB, IHC, ELISA, ICC, IF
Host: Rabbit
Polyclonal
unconjugated
Restrictions
For Research Use only
Target
S100A7
(S100 Calcium Binding Protein A7 (S100A7))
Alternative Name
Psoriasin (S-100 homolog)
Background
Exalpha's anti - human Psoriasin antibody detects psoriasin by both western blot and on formalin and paraffin fixed tissue sections. The staining on tissue sections is both nuclear and cytoplasmic. Although its expression in breast cancer is downregulated (in both preinvasive and invasive cancers) when its expression is maintained in breast cancer the expression of psoriasin is correlated with estrogen receptor negativity and node positivity and therefore with poor prognostic features. Further it is correlated with the degree of inflammation inthe tumor which is consistent with its being a chemotactic factor. Synonyms: psoriasin, S-100 homolog, S100 calcium-binding protein A7.