PP5.2 antibody (C-Term)

Catalog No. ABIN306896

The Rabbit Polyclonal anti-PP5.2 antibody has been validated for WB. It is suitable to detect PP5.2 in samples from Human.

Quick Overview for PP5.2 antibody (C-Term) (ABIN306896)

Target: PP5.2 (Serine/threonine-Protein Phosphatase 5 (PP5.2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PP5.2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PP5.2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT), PPP5C, PPP5,Protein phosphatase 5 (PP5) is a novel human protein serine/threonine phosphatase of molecular weight of 58 kDa. It is made up of a C-terminal phosphatase catalytic domain and an N-terminal domain, which has four repeats of 34 amino acids, three of which are tandemly arranged. The phosphatase domain contains all of the invariant motifs of the PP1/PP2A/PP2B gene family. However, it is not closely related to any other known member of this family of phosphatases. Thus it makes up a new subfamily of phosphatases. PP5 expressed in bacteria has been shown to dephosphorylate serine residues in proteins and is more sensitive than PP1 to the tumor promoter okadaic acid. PP5 appears to be localized to the nucleus suggesting that, like other nuclear tetratricopeptide (TPR)-containing proteins, it may playa role in the regulation of RNA biogenesis and mitosis.

Purification: Ammonium Sulfate Precipitation

Immunogen: Rabbits were immunized with a Synthetic peptide derived from the human protein phosphatase 5 proteins

Isotype: IgG

Application Details

Application Notes: This antibody can be used for Western blotting (5-10 μg/mL). Other applications being evaulated. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for PP5.2

Target: PP5.2 (Serine/threonine-Protein Phosphatase 5 (PP5.2))

Alternative Name: Protein Phosphatase 5