GPR68 antibody

Catalog No. ABIN306927

This anti-GPR68 antibody is a Rabbit Polyclonal antibody detecting GPR68 in WB, IHC and InhA. Suitable for Human.

Quick Overview for GPR68 antibody (ABIN306927)

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR68 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Inhibition Assay (InhA)

Product Details anti-GPR68 Antibody

Cross-Reactivity: Human

Characteristics: GPR68, Ovarian Cancer G Protein-Coupled Receptor 1,OGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC). SPC is a member of a class of bioactive lipids which regulate cellular functions. These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing. SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration. OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes. It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas.

Purification: Protein A/G Chromatography

Immunogen: Rabbits were immunized with recombinant protein derived from human OGR1 (GPR68).

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 μg/mL). Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Alternative Name: OGR1/GPR68

UniProt: Q15743