alpha Fetoprotein antibody

Catalog No. ABIN307022

The Mouse Monoclonal anti-alpha Fetoprotein antibody is suitable to detect alpha Fetoprotein in samples from Human, Pig and Dog. It has been validated for IHC.

Quick Overview for alpha Fetoprotein antibody (ABIN307022)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reactivity: Human, Pig, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Fetoprotein antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: C3

Product Details anti-alpha Fetoprotein Antibody

Purpose: Mouse anti Human Fetoprotein

Cross-Reactivity: Dog, Human, Pig

Characteristics: Alpha-Feto Protein (AFP) is a protein produced by the fetus, which is excreted into the amniotic fluid and into the mother's bloodstream through the placenta. The amount of AFP, both in the maternal79s blood and in the amniotic fluid, at particular periods during the pregnancy, may be associated with the presence of neural tube defects or chromosomal problems in the baby. AFP synthesis occurs in tissues including the gut, liver and fetal yolk sac. AFP expression may be seen in germ cell neoplasma and in liver carcinoma.

Purification: Protein A/G Chromatography

Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with purified human alpha-fetoprotein and mouse myeloma cells.

Isotype: IgG2a

Application Details

Application Notes: Antibody can be used for immunohistochemistry on formalin-fixed, paraffin embedded tissues (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Alternative Name: alpha-Fetoprotein

Background: AFP

Pathways: C21-Steroid Hormone Metabolic Process