CD59 antibody (Biotin)

Catalog No. ABIN3071864

This Mouse Monoclonal antibody specifically detects CD59 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD59 antibody (Biotin) (ABIN3071864)

Target: CD59

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD59 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: BRA-10G

Product Details anti-CD59 Antibody (Biotin)

Purpose: CD59 Biotin Antibody

Characteristics: The clone BRA-10G binds with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis and is a potent inhibitor of the complement membrane attack complex. CD59 is widely distributed on cells in all tissues. The CD59 expression on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions.

Purification: Purified

Purity: >95 %

Immunogen: Human K562 tumor cells

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD59

Target: CD59

Alternative Name: CD59

NCBI Accession: NP_000602, NP_001120695, NP_001120697, NP_001120698, NP_001120699, NP_976074, NP_976075, NP_976076

UniProt: P13987

Pathways: Complement System