CD40 antibody (PE)

Catalog No. ABIN307823

The Rat Monoclonal anti-CD40 antibody has been validated for FACS, IHC and IHC (fro). It is suitable to detect CD40 in samples from Mouse.

Quick Overview for CD40 antibody (PE) (ABIN307823)

Target: CD40

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD40 antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3-23

Product Details anti-CD40 Antibody (PE)

Specificity: Anti-mouse monoclonal antibody (clone 3/23) reacts with CD40 which is expressed on B lymphocytes and on a subset of both CD4+ and CD8+ T cells in the adult (but not neonatal) spleen1. The level of CD40 on B cells is enhanced following activation by LPS1

Purification: Purified

Immunogen: Mouse CD40-human IgG1 fusion protein1 Antibody Concentration: 0.1 mg/ml.

Type of Immunogen: Fusion protein

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo (0.25 μg/10 x10⁶), IHC, IHC-Fr

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.1 % sodium azide, EIA grade BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for CD40

Target: CD40

Alternative Name: CD40

Background: Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

Gene ID: 958

UniProt: P25942

Pathways: NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints