LASS1 antibody (Internal Region)

Catalog No. ABIN308419

This Goat Polyclonal antibody specifically detects LASS1 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for LASS1 antibody (Internal Region) (ABIN308419)

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This LASS1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Grade: Verified

Product Details anti-LASS1 Antibody

Binding Specificity: Internal Region

Purpose: LASS1

Sequence: KDLREYDTAE AQ

Specificity: This antibody is expected to recognize both reported isoforms (NP_067090.1and NP_937850.1).

Cross-Reactivity: Cow, Human, Mouse, Pig

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-KDLREYDTAEAQ, from the internal region of the protein sequence according to NP_067090.1, NP_937850.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx. 37 kDa band observed in Human Brain (Cerebellum, Cerebral Cortex and Frontal Cortex) lysates (calculated MW of 38.0 kDa according to NP_937850.1) An additional band of unknown identity was also consistently observed at 85 kDa. This

Peptide ELISA: antibody detection limit dilution 1:64000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for LASS1

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Alternative Name: CERS1

Background: LAG1, CerS1, LASS1, LAG1 homolog, ceramide synthase 1, MGC90349, UOG1, LAG1 longevity assurance homolog 1, longevity assurance (LAG1, S. cerevisiae) homolog 1, longevity assurance gene 1, upstream of GDF1

Gene ID: 10715, 93898, 306351

NCBI Accession: NP_067090, NP_937850