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ALPL antibody

This Mouse Monoclonal antibody specifically detects ALPL in IHC (p) and EIA. It exhibits reactivity toward Human.
Catalog No. ABIN316660

Quick Overview for ALPL antibody (ABIN316660)

Target

See all ALPL Antibodies
ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reactivity

  • 86
  • 54
  • 21
  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 87
  • 21
  • 1
  • 1
Mouse

Clonality

  • 86
  • 24
Monoclonal

Conjugate

  • 66
  • 9
  • 7
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ALPL antibody is un-conjugated

Application

  • 77
  • 39
  • 36
  • 18
  • 17
  • 14
  • 13
  • 13
  • 13
  • 12
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone

BGN-03-66KF44
  • Specificity

    This antibody is specific for bone and liver Alkaline Phosphatase, a hydrolase enzyme responsible for dephosphorylation of many types of molecules.

    Characteristics

    Synonyms: AP-TNAP, TNSALP, Alkaline phosphatase, tissue-nonspecific isozyme, Alkalinephosphatase liver/bone/kidney isozyme

    Purification

    Purified IgG prepared by affinity chromatography on Protein A

    Immunogen

    Human bone alkaline phosphatase

    Isotype

    IgG3
  • Application Notes

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 0.09 % Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

    Expiry Date

    12 months
  • Target

    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

    Alternative Name

    Alkaline Phosphatase / ALPL

    Background

    Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH . Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.Synonyms: AP-TNAP, Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, TNSALP, tissue-nonspecific isozyme

    Gene ID

    249

    UniProt

    P05186
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