CD51 antibody
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- Target See all CD51 (ITGAV) Antibodies
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD51 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Characteristics
- Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
- Purification
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.
- Endotoxin Level
- Low Endotoxin
- Immunogen
- cultured LAK cells from Balb/c mice.
- Clone
- RMV-7
- Isotype
- IgG1
- Top Product
- Discover our top product ITGAV Primary Antibody
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- Application Notes
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Flow Cytometry: 1/10 - 1/100. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0mg/mL
- Buffer
- Phosphate buffered saline pH 7.4
- Storage
- -20 °C
- Storage Comment
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: - Expiry Date
- 12 months
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- Target
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Alternative Name
- CD51 / ITGAV (ITGAV Products)
- Background
- CD51 is a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the intergrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing.Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha
- UniProt
- P43406
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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