CD51 antibody

Catalog No. ABIN316870

This Rat Monoclonal antibody specifically detects CD51 in FACS, IP and Func. It exhibits reactivity toward Mouse.

Quick Overview for CD51 antibody (ABIN316870)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD51 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Clone: RMV-7

Product Details anti-CD51 Antibody

Characteristics: Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

Endotoxin Level: Low Endotoxin

Immunogen: cultured LAK cells from Balb/c mice.

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: 1/10 - 1/100. Immunoprecipitation. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline pH 7.4

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution:

Expiry Date: 12 months

Target Details for CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Alternative Name: CD51 / ITGAV

Background: CD51 is a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the intergrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing.Synonyms: Integrin alpha-V, MSK8, VNRA, Vitronectin receptor subunit alpha

UniProt: P43406

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex