MHC Class II antibody

Catalog No. ABIN317435

The Mouse Monoclonal anti-MHC Class II antibody has been validated for FACS, WB and EIA. It is suitable to detect MHC Class II in samples from Cat.

Quick Overview for MHC Class II antibody (ABIN317435)

Target: MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

Reactivity: Cat

Host: Mouse

Clonality: Monoclonal

Conjugate: This MHC Class II antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: PF6J-6D

Product Details anti-MHC Class II Antibody

Purification: Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry. ELISA: Can be used in ELISA in conjunction with ABIN317436 (clone PF8J-9B). Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline pH 7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing. Should this product contain a precipitate we recommendmicrocentrifugation before use.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for MHC Class II

Target: MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

Alternative Name: MHC Class II

Background: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In cats, this is referred to as the feline leukocyte antigen (FLA) region. The complex retrovirus FIV (feline immunodeficiency virus), is responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency virus (HIV). Studies have shown that the intensity of MHC Class II expression on cat lymphocyte membranes has been found to vary in association with feline retrovirus infections.Synonyms: HLA Class II, Human Leukocyte antigen class II, MHC Class 2, Major histocompatibility complex class II