RPL10 antibody

Catalog No. ABIN317605

This Rabbit Polyclonal antibody specifically detects RPL10 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RPL10 antibody (ABIN317605)

Target: RPL10 (Ribosomal Protein L10 (RPL10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPL10 Antibody

Specificity: This antibody detects endogenous levels of QM protein.(region surrounding Phe34)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western Blot: 1/500-1/1000. ELISA: 1/20000-1/40000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for RPL10

Target: RPL10 (Ribosomal Protein L10 (RPL10))

Alternative Name: RPL10

Background: The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. A distant member of the MAP kinase family, designated c-Jun NH2-terminal kinase (JNK1) functions to regulate c-Jun by phosphorylation at the amino terminal serine regulatory sites, Ser 63 and Ser 73). QM has been described as a transcription factor that can function to bind DNA directly or alternatively can interact with c-Jun to inhibit transactivation of AP-1 promoter driven reporter vectors by Jun-Jun homodimers. QM is highly conserved throughout eukaryotic evolution and is apparently a member of a multi-gene family.Synonyms: 60S ribosomal protein L10, DXS648E, Laminin receptor homolog, QM, Tumor suppressor QM

Gene ID: 6134

NCBI Accession: NP_006004

UniProt: P27635