Meningioma 1 antibody

Catalog No. ABIN317611

This Rabbit Polyclonal antibody specifically detects Meningioma 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Meningioma 1 antibody (ABIN317611)

Target: Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Meningioma 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Meningioma 1 Antibody

Specificity: This antibody detects endogenous levels of MN1 protein.(region surrounding Lys850)

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western Blot: 1/500-1/1000. ELISA: 1/40000-1/60000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Meningioma 1

Target: Meningioma 1 (MN1) (MN1 proto-oncogene (MN1))

Alternative Name: MN1

Background: The MN1 gene, which resides on chromosome 22, encodes a 1,319 amino acid protein. The ETV6/TEL gene has been reported to fuse to MN1. The MN1-TEL fusion protein, encoded by the translocation (12,22)(p13,q11) in myeloid leukemia, is a transcription factor with transforming activity. Defects in MN1 (meningioma 1) may be a cause of meningiomas, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord.Synonyms: Probable tumor suppressor protein MN1, meningioma 1

Gene ID: 4330

NCBI Accession: NP_002421

UniProt: Q10571