BRS3 antibody

Catalog No. ABIN317729

The Rabbit Polyclonal anti-BRS3 antibody is suitable to detect BRS3 in samples from Human. It has been validated for WB, IF and EIA.

Quick Overview for BRS3 antibody (ABIN317729)

Target: BRS3 (Bombesin-Like Receptor 3 (BRS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-BRS3 Antibody

Specificity: This antibody detects endogenous levels of BRS3 (region surrounding Cys203).

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity-chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BRS3

Target: BRS3 (Bombesin-Like Receptor 3 (BRS3))

Alternative Name: BRS3

Background: Bombesin receptor subtype-3 (BRS3) is an integral membrane protein belonging to the G protein-coupled receptor 1 family. The gene encoding for the BRS3 protein maps against chromosome Xq26-q28. BRS3 is important in sperm cell division, maturation and function. Its actions are mediated by G protein interactions which activate a phosphatidylinositol-calcium second messenger system. BRS3 is expressed in germ cells in testis and in lung carcinoma cells. Unlike other bombesin proteins, BRS3 does not seem to be detected in the gut and central nervous system, but has been found in rat gastrointestinal tract. Mice lacking the gene encoding for BRS3 develop obesity, suggesting that BRS3 may play a role in the regulation of plasma insulin concentration.Synonyms: BRS-3, Bombesin receptor subtype-3

Molecular Weight: approx. 44 kDa

Gene ID: 680

NCBI Accession: NP_001718

UniProt: P32247

Pathways: Feeding Behaviour