CCKBR antibody

Catalog No. ABIN317856

This anti-CCKBR antibody is a Rabbit Polyclonal antibody detecting CCKBR in WB. Suitable for Human, Mouse and Rat.

Quick Overview for CCKBR antibody (ABIN317856)

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKBR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCKBR Antibody

Specificity: This antibody detects endogenous levels of CCK-BR protein.(region surrounding Leu54)

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CCKBR

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Alternative Name: CCK-B Receptor

Background: CCKBR is a G protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR is most abundant in brain and stomach but it can also be found in colon, pancreas, thyroid, and various cancers.Synonyms: CCK-BR, CCK2-R, CCKB Receptor, CCKBR, CCKRB, Cholecystokinin type B receptor, Cholecystokinin-2 receptor, Gastrin/cholecystokinin type B receptor

Molecular Weight: approx. 52 kDa

Gene ID: 887

NCBI Accession: NP_795344

UniProt: P32239

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour