CD59 antibody (PE)

Catalog No. ABIN320332

This Mouse Monoclonal antibody specifically detects CD59 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD59 antibody (PE) (ABIN320332)

Target: CD59

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD59 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: MEM-43-5

Product Details anti-CD59 Antibody (PE)

Specificity: This antibody reacts with a PI-linked glycoprotein, Mw 18-20 kDa found on all types of leucocytes including platelets. The antigen is expressed on many haemopoietic and non-haemopoietic cells.

Purification: Purified IgG prepared by affinity chromatography on Protein A

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry: Use 10 μL of Neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.25 mL distilled water.

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted Prior to and after reconstitution at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch. Reconstitution: Restore with 1.0 ml distilled water..

Expiry Date: 12 months

Target Details for CD59

Target: CD59

Alternative Name: CD59

Background: CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

Gene ID: 966

UniProt: P13987

Pathways: Complement System