IL-6 Receptor antibody (Extracellular Domain)

Catalog No. ABIN327368

The Rat Monoclonal anti-IL-6 Receptor antibody has been validated for WB and ELISA. It is suitable to detect IL-6 Receptor in samples from Mouse.

Quick Overview for IL-6 Receptor antibody (Extracellular Domain) (ABIN327368)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL-6 Receptor Antibody

Binding Specificity: Extracellular Domain

Specificity: Recognizes mouse IL-6Ralpha. In direct ELISAs and Western Blots, this antibody does not cross-react with rhIL-6R.

Purification: Protein G purified

Immunogen: NS0-derived rmIL-6Ralpha extracellular domain (aa 20-357) P22272

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, WB

Usage: Western Blot: This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect mouse IL-6 R. Using a colorimetric detection system, the detection limit for rmIL-6 R is approximately 25 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect mouse IL-6 R. The detection limit for rmIL-6 R is approximately 5 ng/well.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 200 μL sterile PBS

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose.

Handling Advice: Avoid freeze-thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL6R / IL6 Receptor

Background: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

Gene ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints