Lysine (K)-Specific Methyltransferase 2A (KMT2A) (AA 720-780), (N-Term) antibody

Catalog No. ABIN328575

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB, IHC, FACS and IHC (p). Suitable for Human and Mouse.

Quick Overview for Lysine (K)-Specific Methyltransferase 2A (KMT2A) (AA 720-780), (N-Term) antibody (ABIN328575)

Target: Lysine (K)-Specific Methyltransferase 2A (KMT2A)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 720-780, N-Term

Specificity: Specific for human MLL1 protein. Species cross-reactivity: mouse. Other species have not been tested.

Purification: Immunoaffinity purified

Immunogen: A synthetic peptide mapping to a region between residues 720 and 780 of human myeloid/lymphoid or mixed-lineage leukemia 1 using the number given in Swiss-Prot entry Q03164 (GeneID 4297). The epitope is found in the N-terminal 300 kD fragment generated by proteolytic cleavage. The epitope is found in isoform 14P-18B of MLL1.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Flo, IHC, IHC-P, WB

Usage: Suitable for use in Western Blot, and Immunohistochemistry (paraffin-embedded sections).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate,  pH 7.5, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details

Target: Lysine (K)-Specific Methyltransferase 2A (KMT2A)

Alternative Name: KMT2A / MLL

Background: Name/Gene ID: KMT2A

Synonyms: KMT2A, ALL1, CDK6/MLL fusion protein, FLJ11783, HRX, HTRX, HTRX1, Lysine N-methyltransferase 2A, MLL1A, MLL/GAS7, MLL1, ALL-1, MLL, MLL/GAS7 fusion protein, TRX1, WDSTS, Trithorax-like protein, Zinc finger protein HRX, CXXC7, MLL-AF4 der(11) fusion protein, MLL/GMPS fusion protein, TET1-MLL

Gene ID: 4297

UniProt: Q03164

Pathways: Warburg Effect