Anti-ASY1 | Asynaptic phenotype protein 1 (monoclonal)
Cross-Reactivity (Details)
Triticum aestivum Not reactive in: No confirmed exceptions from predicted reactivity are currently known
Predicted Reactivity
Triticum aestivum
Purification
Protein G purified
Immunogen
KLH-conjugated synthetic pepitde chosen from Triticum aestivum ASY1 UniProt: A7TVU8
Application Notes
1: 10 000 (ELISA), 1: 1000 (WB)
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
For reconstitution add 50 μL of sterile water/tube
Buffer
Total IgG. Protein G purified purified from Cell culture supernatant.
Handling Advice
Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube
Storage
-20 °C
Storage Comment
Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Target
ASY1
(DNA-Binding HORMA Protein (ASY1))
Alternative Name
ASY1
Background
Pairing and synapsis of homologous chromosomes is required for normal chromosome segregation and the exchange of genetic material via recombination during meiosis. Synapsis is complete at pachytene following the formation of a tri-partite proteinaceous structure known as the synaptonemal complex (SC). In yeast, HOP1 is essential for formation of the SC, and localises along chromosome axes during prophase I. Homologues in Arabidopsis (AtASY1), Brassica (BoASY1) and rice (OsPAIR2) have been isolated through analysis of mutants that display decreased fertility due to severely reduced synapsis of homologous chromosomes. Analysis of these genes has indicated that they play a similar role to HOP1 in pairing and formation of the SC through localisation to axial/lateral elements of the SC.