TREM2 antibody (AA 19-161)

Catalog No. ABIN336080

The Mouse Monoclonal anti-TREM2 antibody has been validated for WB and EIA. It is suitable to detect TREM2 in samples from Mouse and Human.

Quick Overview for TREM2 antibody (AA 19-161) (ABIN336080)

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Reactivity: Mouse, Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TREM2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 2B5

Product Details anti-TREM2 Antibody

Binding Specificity: AA 19-161

Specificity: The antibody recognizes Human and Mouse TREM2. Other species not tested.

Characteristics: Synonyms: TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on myeloid cells 2,Triggering receptor expressed on monocytes 2

Purification: Protein-G Affinity Chromatography

Immunogen: Recombinant human TREM2 (19-161 aa) purified from E. coli

Isotype: IgG3

Application Details

Application Notes: ELISA. Western blot (1/500-1/1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for TREM2

Target: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Alternative Name: TREM2

Background: The triggering receptor expressed on myeloid cells-2 (TREM2) is a membrane protein that interacts with the TYROBP protein. The TREM2 and TYROBP proteins form a complex that transmits chemical signals to activate the cell. This complex is involved in the growth and development of several types of immune cells, particularly dendritic cells and activates these cells, triggering an inflammatory response to injury or disease. And the TYROBP-TREM2 complex also activates cells in the skeletal system and in the brain and spinal cord (central nervous system).Synonyms: TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells 2

Gene ID: 54209

UniProt: Q9NZC2