TSH antibody

Catalog No. ABIN336912

This anti-TSH antibody is a Mouse Monoclonal antibody detecting TSH in IHC and IHC (p). Suitable for Human.

Quick Overview for TSH antibody (ABIN336912)

Target: TSH (Thyroid Stimulating Hormone (TSH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TSH antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TSH220

Product Details anti-TSH Antibody

Specificity: Molecular Weight: Beta (beta) 14 kDa, alpha+Beta (alpha+beta) 28 kDa.

Immunogen: Human TSH, beta subunit

Isotype: IgG1

Application Details

Application Notes: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) Dilute conc. antibodies 1:50-1:100 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. For FFPE tissue sections, the intensity of staining can be enhanced by antigen retriever (boiling tissue in 10 mM citrate, pH 6.0 for 15-20 mins, followed by cooling at RT for 20 mins). The optimum dilution should be determined by the individual lab. Positive Control: Human Anterior pituitary. Cellular Localization: Cytoplasmic staining of anterior pituitary cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibodies are supplied with 1% BSA in PBS with 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for TSH

Target: TSH (Thyroid Stimulating Hormone (TSH))

Alternative Name: TSH

Target Type: Hormone

Background: Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta subunit. The alpha (alpha) subunit is identical to that of human chorionic gonadotropin (HCG), luteinizing hormone (LH), follicle-stimulating hormone (FSH). The beta (beta) subunit is unique to TSH, and therefore determines its function. This antibody labels thyrotrophic cells of the pituitary and may be useful for research in the classification of pituitary adenocarcinomas and differential identification of primary and metastatic tumors of the pituitary.