LH antibody

Catalog No. ABIN336992

The Rabbit Polyclonal anti-LH antibody is suitable to detect LH in samples from Human. It has been validated for IHC (p) and IHC.

Quick Overview for LH antibody (ABIN336992)

Target: LH

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC)

Product Details

Immunogen: LH beta

Application Details

Application Notes: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. The optimum dilution should be determined by the individual lab. Positive Control: Human anterior pituitary. Cellular Localization: Cytoplasmic.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Protein A purified total IgG in 10 mM PO4, 150 mM NaCl, and pH 7.4, 1% BSA, 0.05% % sodium azide HostRabbit Intended Use Immunohistochemistry (IHC) and Immunocytchemistry (ICC)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details

Target: LH

Background: Luteinizing hormone (LH) is a tropic hormone which modulates the secretory activity of other endocrine glands. This glycoprotein hormone is produced in the anterior hypophysis of the pituitary gland. In the female an acute rise of LH the LH surge – triggers ovulation. In the male, where LH had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids, the beta subunit vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action. and is responsible for interaction with the LH receptor. This antibody stains both free and intact LH and is useful for the classification of pituitary adenomas and tumors of the pituitary.