LRP1 antibody
Quick Overview for LRP1 antibody (ABIN337070)
Target
See all LRP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Brand
- IHC-plus™
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Specificity
- Recognizes human CD91, a type I membrane protein which is also known as the alpha 2 macroglobulin receptor (alpha 2 MR). Recognizes an epitope in the extracellular region of the 500kD alpha chain.
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Purification
- Protein G purified
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Immunogen
- Purified alpha 2 macroglobulin receptor.
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Isotype
- IgG1
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Application Notes
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Approved: ELISA, Flo, IHC, IHC-Fr, IHC-P (5 - 10 μg/mL), IP, WB
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5-10 μg/mL. Flow Cytometry: 1:50-1:100. Use 10 μL to label 10^6 cells in 100 μL. Western Blot: non-reducing conditions. Positive control: Liver. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
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Alternative Name
- LRP1 / CD91
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Background
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Name/Gene ID: LRP1
Synonyms: LRP1, Apolipoprotein E receptor, CD91 antigen, CD91, A2MR, IGFBP3R, Alpha-2-macroglobulin receptor, TGFBR5, Type V tgf-beta receptor, APOER, APR, LRP, LRP-1 -
Gene ID
- 4035
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UniProt
- Q07954
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Pathways
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Target
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