ABCA4 antibody (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4) (AA 2250-2263)

Catalog No. ABIN343052

Product Details anti-ABCA4 Antibody

Target: ABCA4

See all ABCA4 Antibodies

Binding Specificity: AA 2250-2263

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ABCA4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: ABCA4

Sequence: KQQTESHDLP LHPR

Predicted Reactivity: Human, Dog

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Synthetic peptide C-KQQTESHDLPLHPR from the C-terminus of human ABCA4 (NP_000341.2).
Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-ABCA4 antibody (ABIN343052)

McClements, Barnard, Issa, MacLaren: "Assessment of AAV Dual Vector Safety in theAbca4-/- Mouse Model of Stargardt Disease." in: Translational vision science & technology, Vol. 9, Issue 7, pp. 20, 2020 (PubMed).

McClements, Barnard, Singh, Charbel Issa, Jiang, Radu, MacLaren: "An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4-/- Mice." in: Human gene therapy, Vol. 30, Issue 5, pp. 590-600, 2019 (PubMed).

Lenis, Hu, Ng, Jiang, Sarfare, Lloyd, Esposito, Samuel, Jaworski, Bok, Finnemann, Radeke, Redmond, Travis, Radu: "Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 47, pp. E11120-E11127, 2019 (PubMed).

Target Details for ABCA4

Target: ABCA4

See all ABCA4 Antibodies

Alternative Name: ABCA4 (ABCA4 Antibody Abstract)

Synonyms: ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1, AW050280, Abc10, Abcr, D430003I15Rik, RmP, abcr, ffm, rmp, rp19, stgd, abc10, armd2, cord3, stgd1, zgc:91823, ATP binding cassette subfamily A member 4, ATP-binding cassette, sub-family A (ABC1), member 4, ATP binding cassette subfamily A member 4 L homeolog, ATP-binding cassette, sub-family A (ABC1), member 4a, ABCA4, Abca4, abca4, abca4.L, abca4a

Background: ABCA4, ATP-binding cassette, sub-family A (ABC1), member 4, ABC10, ABCR, ARMD2, CORD3, DKFZp781N1972, FFM, RMP, RP19, STGD, STGD1, ATP binding cassette transporter, ATP-binding cassette, sub-family A member 4, ATP-binding transporter, retina-specific, retina-specific ABC transporter, rim protein

Gene ID: 24

NCBI Accession: NP_000341

UniProt: P78363