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ABCA4 antibody (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4) (AA 2250-2263) Primary Antibody

ABCA4 Reactivity: Human ELISA, WB Host: Goat Polyclonal unconjugated
Pubmed (3)
Catalog No. ABIN343052
$481.84
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100 μg
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  • Target
    ABCA4
    Binding Specificity
    AA 2250-2263
    Reactivity
    Human
    Host
    Goat
    Clonality
    Polyclonal
    Conjugate
    This ABCA4 antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB)
    Purpose
    ABCA4
    Sequence
    KQQTESHDLP LHPR
    Predicted Reactivity
    Human, Dog
    Purification
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Grade
    Verified
    Immunogen
    Synthetic peptide C-KQQTESHDLPLHPR from the C-terminus of human ABCA4 (NP_000341.2).
    Type of Immunogen: Synthetic peptide
    Isotype
    IgG
  • Application Notes
    Peptide ELISA: antibody detection limit dilution 1:8000.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Minimize freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • McClements, Barnard, Issa, MacLaren: "Assessment of AAV Dual Vector Safety in theAbca4-/- Mouse Model of Stargardt Disease." in: Translational vision science & technology, Vol. 9, Issue 7, pp. 20, 2020 (PubMed).

    McClements, Barnard, Singh, Charbel Issa, Jiang, Radu, MacLaren: "An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4-/- Mice." in: Human gene therapy, Vol. 30, Issue 5, pp. 590-600, 2019 (PubMed).

    Lenis, Hu, Ng, Jiang, Sarfare, Lloyd, Esposito, Samuel, Jaworski, Bok, Finnemann, Radeke, Redmond, Travis, Radu: "Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 47, pp. E11120-E11127, 2019 (PubMed).

  • Target
    ABCA4
    Alternative Name
    ABCA4 (ABCA4 Antibody Abstract)
    Synonyms
    ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1, AW050280, Abc10, Abcr, D430003I15Rik, RmP, abcr, ffm, rmp, rp19, stgd, abc10, armd2, cord3, stgd1, zgc:91823, ATP binding cassette subfamily A member 4, ATP-binding cassette, sub-family A (ABC1), member 4, ATP binding cassette subfamily A member 4 L homeolog, ATP-binding cassette, sub-family A (ABC1), member 4a, ABCA4, Abca4, abca4, abca4.L, abca4a
    Background
    ABCA4, ATP-binding cassette, sub-family A (ABC1), member 4, ABC10, ABCR, ARMD2, CORD3, DKFZp781N1972, FFM, RMP, RP19, STGD, STGD1, ATP binding cassette transporter, ATP-binding cassette, sub-family A member 4, ATP-binding transporter, retina-specific, retina-specific ABC transporter, rim protein
    Gene ID
    24
    NCBI Accession
    NP_000341
    UniProt
    P78363
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