MAF antibody

Catalog No. ABIN346926

This Rabbit Polyclonal antibody specifically detects MAF in WB, ELISA, IHC and IEM. It exhibits reactivity toward Human.

Quick Overview for MAF antibody (ABIN346926)

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoelectron Microscopy (IEM)

Product Details anti-MAF Antibody

Specificity: Reacts with human 47 kDa Maf protein derived from a transfected CEFcell line

Purification: Antiserum

Immunogen: Maf-GST fusion protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/50 to 1/500 - WB : 1/200 to 1/5 000 Useful for electrophoretic mobility shift assay (EMSA)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for MAF

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Alternative Name: Transcription Factor Maf

Background: Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

NCBI Accession: NP_001026974

UniProt: O75444