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Histone 3 (H3) (ciArg17), (ciArg2), (ciArg8) antibody Primary Antibody

H3 Reactivity: Human ELISA, ICC, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN347088
$574.08
Plus shipping costs $45.00
200 μL ABIN347088
200 μL ABIN347088
local_shipping Shipping to: United States
Delivery in 6 to 7 Business Days
  • Target
    Histone 3 (H3)
    Binding Specificity
    ciArg2, ciArg8, ciArg17
    • 65
    • 50
    • 49
    • 48
    • 43
    • 43
    • 42
    • 37
    • 37
    • 36
    • 35
    • 34
    • 34
    • 34
    • 31
    • 29
    • 28
    • 25
    • 23
    • 21
    • 20
    • 20
    • 19
    • 18
    • 17
    • 17
    • 17
    • 17
    • 16
    • 15
    • 15
    • 15
    • 14
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 12
    • 11
    • 11
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reactivity
    Human
    • 1437
    • 973
    • 906
    • 62
    • 56
    • 42
    • 41
    • 41
    • 41
    • 40
    • 37
    • 35
    • 35
    • 25
    • 22
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    • 1219
    • 282
    • 9
    • 5
    • 1
    Clonality
    Polyclonal
    • 1134
    • 379
    Conjugate
    Un-conjugated
    • 862
    • 83
    • 66
    • 61
    • 61
    • 61
    • 60
    • 60
    • 34
    • 34
    • 21
    • 17
    • 17
    • 17
    • 17
    • 17
    • 13
    • 13
    • 2
    Application
    ELISA, Immunocytochemistry (ICC), Immunohistochemistry (IHC), Western Blotting (WB)
    • 1029
    • 444
    • 360
    • 341
    • 332
    • 221
    • 191
    • 170
    • 151
    • 147
    • 122
    • 104
    • 101
    • 42
    • 38
    • 33
    • 25
    • 22
    • 12
    • 12
    • 8
    • 7
    • 6
    • 1
    • 1
    Specificity
    Reacts with human Histone H3 Citrulline at the 3 positions: 2, 8 and 17
    Cross-Reactivity (Details)
    Reacts with mono or di H3-Cit. Not tested in other species. May cross reacts with other species due to sequence homology.
    Purification
    Antiserum
    Immunogen
    Synthetic peptide derived from Nter domain of human Histone H3 containing Citrulline at position 2-8-17
    Isotype
    IgG
  • Application Notes

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    - IHC : 1/2 000 to 1/20 000 - WB : 1/5 000 to 1/50 000

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Must be reconstituted in distilled water.
    Storage
    4 °C/-20 °C
    Storage Comment
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Expiry Date
    24 months
  • Target
    Histone 3 (H3)
    Alternative Name
    Histone H3 ()
    Synonyms
    H-3, histocompatibility 3, H3
    Background
    This core component of the nucleosome can be citrullinated on arginines 2, 8 and 17 by PADI4. These modifications blocks methylation and so represses the transcription
    Gene ID
    440093
    UniProt
    Q6NXT2
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