Podoplanin antibody (Internal Region)

Catalog No. ABIN347107

This Rabbit Polyclonal antibody specifically detects Podoplanin in WB, IHC, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for Podoplanin antibody (Internal Region) (ABIN347107)

Target: Podoplanin (PDPN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Podoplanin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-Podoplanin Antibody

Binding Specificity: Internal Region

Specificity: Reacts with human podoplanin

Purification: Antiserum

Immunogen: Synthetic peptide derived from internal region of human Podoplanin

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- FC : 1/100 to 1/500 - IHC : 1/50 to 1/500 - WB : 1/200 to 1/1 000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for Podoplanin

Target: Podoplanin (PDPN)

Alternative Name: Podoplanin

Background: May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport