TPCN1 antibody (AA 750-800)

Catalog No. ABIN350015

The Rabbit Polyclonal anti-TPCN1 antibody has been validated for WB and IHC. It is suitable to detect TPCN1 in samples from Mouse.

Quick Overview for TPCN1 antibody (AA 750-800) (ABIN350015)

Target: TPCN1 (Two Pore Segment Channel 1 (TPCN1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPCN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TPCN1 Antibody

Binding Specificity: AA 750-800

Purpose: Rabbit antibody to TPC1 (750-800)

Specificity: Specific for TPC1.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from AA 750-800 of mouse TPC1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and shares 98% identity with human sequence.

Isotype: IgG

Application Details

Application Notes: IHC WB (confirmed by recombinant protein). A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for TPCN1

Target: TPCN1 (Two Pore Segment Channel 1 (TPCN1))

Alternative Name: TPC1

Background: Function: May function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Subcellular location: Membrane, Multi-pass membrane protein. Tissue specificity: Highest expression found in the heart and kidney and lowest expression found in the spleen.

UniProt: Q9EQJ0