TMEM166 antibody

Catalog No. ABIN350019

Product Details anti-TMEM166 Antibody

Target: TMEM166 (FAM176A) (Family with Sequence Similarity 176, Member A (FAM176A))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This TMEM166 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Sheep antibody to TMEM166

Specificity: Specific for TMEM166.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from human transmembrane protein 166 (TM166 TMEM166) conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Application Details

Application Notes: IHC WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for TMEM166

Target: TMEM166 (FAM176A) (Family with Sequence Similarity 176, Member A (FAM176A))

Alternative Name: TMEM166 (FAM176A Products)

Background: FUNCTION: Acts as a regulator of programmed cell death mediating both autophagy and apoptosis. SUBCELLULAR LOCATION: Endoplasmic reticulum membrane, Single-pass membrane protein. Lysosome membrane, Single-pass membrane protein. TISSUE SPECIFICITY: Expressed in lung kidney liver pancreas placenta but not in heart and skeletal muscle.

UniProt: Q9H8M9