COPD (AA 150-200) antibody

Catalog No. ABIN350257

This Rabbit Polyclonal antibody specifically detects in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for COPD (AA 150-200) antibody (ABIN350257)

Target: COPD

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 150-200

Purpose: Rabbit antibody to COPD (150-200)

Specificity: Specific for COPD.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from AA 150-200 of human COPD conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat mouse and xenopus.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details

Target: COPD

Background: FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles which further mediate biosynthetic protein transport from the ER via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs) which are small GTP-binding proteins, the complex also influences the Golgi structural integrity as well as the processing activity and endocytic recycling of LDL receptors. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein, Cytoplasmic side. Cytoplasmic vesicle COPI-coated vesicle membrane, Peripheral membrane protein, Cytoplasmic side. Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi as well as on the vesicles/buds originating from it.

UniProt: P48444