DOC2B antibody (Internal Region)

Catalog No. ABIN350293

Product Details anti-DOC2B Antibody

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Binding Specificity: Internal Region

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOC2B antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit antibody to Doc2b

Specificity: Specific for DOC2B.

Cross-Reactivity: Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from internal region of rat Doc2b conjugated to an immunogenic carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for DOC2B

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Alternative Name: Doc2b (DOC2B Products)

Background: FUNCTION: May be involved in constitutive membrane trafficking including dynein-dependent intracellular vesicle transport. In vitro binds calcium and phospholipids. SUBCELLULAR LOCATION: Membrane, Peripheral membrane protein. TISSUE SPECIFICITY: Widely expressed.

UniProt: P70610

Pathways: Positive Regulation of Peptide Hormone Secretion