Myeloperoxidase antibody

Catalog No. ABIN350505

The Rabbit Polyclonal anti-Myeloperoxidase antibody (ABIN350505) specifically detects Myeloperoxidase in WB, IHC and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Myeloperoxidase antibody (ABIN350505)

Target: Myeloperoxidase (MPO)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myeloperoxidase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Myeloperoxidase Antibody

Purpose: Rabbit antibody to MPO

Specificity: Specific for MPO.

Cross-Reactivity: Human

Purification: Protein G purified IgG

Immunogen: Native myeloperoxidase isolated from human leucocytes

Isotype: IgG

Application Details

Application Notes: IHC WB. A working concentration of 10-50 μg,ml is recommended. The optimal dilution should be determined by the end user. This antibody performs superbly in paraffin-embedded tissue sections fixed in formalin frozen sections,cell cytospins.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: MPO

Background: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. SUBCELLULAR LOCATION: Lysosome

UniProt: P05164

Pathways: Chromatin Binding