PRTN3 antibody (C-Term)

Catalog No. ABIN350764

This Rabbit Polyclonal antibody specifically detects PRTN3 in WB, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for PRTN3 antibody (C-Term) (ABIN350764)

Target: PRTN3 (Proteinase 3 (PRTN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRTN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-PRTN3 Antibody

Binding Specificity: C-Term

Purpose: Rabbit antibody to Pr3

Specificity: Specific for Pr3.

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from the c-terminal region of human Pr3 (Leukocyte proteinase 3 AGP7 Myeloblastin Wegener autoantigen) conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: WB IHC flow cytometry. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for PRTN3

Target: PRTN3 (Proteinase 3 (PRTN3))

Alternative Name: Pr3

Background: FUNCTION: Polymorphonuclear leukocyte serine protease that degrades elastin fibronectin laminin vitronectin and collagen types I III and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Catalytic activity: Hydrolysis of proteins including elastin by preferential cleavage: -Ala-|-Xaa- > -Val-|-Xaa-.

UniProt: P24158