RND1 antibody

Catalog No. ABIN350794

Product Details anti-RND1 Antibody

Target: RND1 (rho Family GTPase 1 (RND1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RND1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit antibody to Rho6

Specificity: Specific for RND1.

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: Synthetic peptides (dimer) from human Rho related GTP binding protein Rho6 (RND1) conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for RND1

Target: RND1 (rho Family GTPase 1 (RND1))

Alternative Name: Rho6 (RND1 Products)

Background: Function: Lacks intrinsic GTPase activity. Has a low affinity for GDP and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Cytoplasm ‰ cytoskeleton. Tissue specificity: Mostly expressed in brain and liver.

UniProt: Q92730